February 29, 2012Circulation
Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation
Why the study?
Are elevations of troponin I and NT-proBNP associated with an increased risk of stroke and mortality in patients with atrial fibrillation?
Population
Patients with atrial fibrillation
Design
Cohort
Authors
Discussion
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Member takes
Implication
May refine AF stroke/mortality risk prediction beyond clinical scores; hypothesis-generating, requiring prospective validation before practice change.
Structured PICO
Are elevations of troponin I and NT-proBNP associated with an increased risk of stroke and mortality in patients with atrial fibrillation?
P
Population
Patients with atrial fibrillation
I
Intervention
Elevated cardiac biomarkers (troponin I and NT-proBNP)
O
Outcome
Stroke and mortalityhard clinical
Cardiac biomarkers such as troponin I and NT-proBNP may improve risk prediction for stroke and mortality in patients with atrial fibrillation beyond currently used clinical variables.
Cite This Study
Hijazi et al. (2012) studied this question.