Why the study?
Does the ABC biomarker-based risk score improve prognostication of stroke in patients with atrial fibrillation?
Does the ABC biomarker-based risk score improve prognostication of stroke in patients with atrial fibrillation?
The ABC stroke risk score aims to improve stroke prognostication in atrial fibrillation by incorporating cardiac biomarkers (NT-proBNP and cTn-hs) alongside age and clinical history.
May refine AF stroke risk stratification; leaves open whether biomarker integration improves outcomes or should change practice.
Atrial fibrillation (AF) is associated with an increased risk of stroke, which is currently estimated by clinical characteristics. The cardiac biomarkers N-terminal fragment B-type natriuretic peptide (NT-proBNP) and cardiac troponin highsensitivity (cTn-hs) are independently associated with risk of stroke in AF. Our objective was to develop and validate a new biomarker-based risk score to improve prognostication of stroke in patients with AF.
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Hijazi et al. (2016) studied this question.
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