Case report reveals 14-year delayed extracranial metastases in atypical meningioma, suggesting aggressive behavior.
Meningioma, one of the most common neoplasms of the central nervous system in adults, is most likely derived from the meningothelial cells of the arachnoid matter. Although most meningiomas have a benign clinical course and a relatively good prognosis, some can demonstrate more aggressive biological features, including local invasion and distant metastases. Extracranial meningioma metastases are rare, occurring in less than 1% of cases. We present a case of atypical meningioma status post resection with intracranial recurrence followed by multiple radiation therapies who developed extracranial metastases 14 years after primary tumor resection.
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Firde et al. (2026) studied this question.
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