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March 1, 2026NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES

Evaluation of Depression in Multiple Sclerosis Patients in Lithuania

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Authors

RLRytis Leonavičius

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Overview

Evaluation reveals prevalence of depression linked to disability status in multiple sclerosis patients, suggesting need for further study.

Key Points

  • To estimate the prevalence of depression in multiple sclerosis patients and its relation to clinical factors.
  • Evaluated 270 patients with multiple sclerosis based on McDonald criteria.
  • Measured depression using the Hamilton Rating Scale for Depression.
  • Assessed disability status with the Expanded Disability Status Scale.
  • Conducted statistical analysis including correlation and regression.
  • 20.7% of patients diagnosed with depression: 2.6% mild, 7.0% moderate, 11.1% severe.
  • Patients with higher disability (EDSS > 4) had a 3.2 times higher odds of depression.
  • No correlation found between depression and clinical factors such as disease duration or course of MS.

Cite This Study

Rytis Leonavičius (2011) studied this question.

synapsesocial.com/papers/69a3d7eeec16d51705d2e663https://doi.org/10.1111/j.1468-1331.2011.03552.x/pdf
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Depression in multiple sclerosis and associated factors2025
  2. 2Relapsing-remitting multiple sclerosis understanding the disability-depression connection2026
  3. 3Prevalence, treatment and correlates of depression in multiple sclerosis2024 · 29 citations
  4. 4Problems of depression in neurological practice2024 · 1 citations
  5. 5Multifactorial model of predictors of the development of depressive disorders in multiple sclerosis: a prospective longitudinal study2024 · 1 citations