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March 1, 2026Open Access

Unveiling the potential antidiabetic, antidyslipidemic, and antimicrobial effects of methanolic root extracts of Nymphaea pubescens Willd. plant: Evidence from in-vitro and in-vivo approaches

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Authors

SSSahid Ahmad SantoTDTanmay DebMSMd. Abdus Salam

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Overview

In-vitro and in-vivo approaches reveal the therapeutic potential of Nymphaea pubescens in lowering blood glucose and cholesterol levels, suggesting a novel treatment option.

Key Points

  • The research aims to evaluate the therapeutic effects of methanolic root extracts of Nymphaea pubescens on diabetes, lipid levels, and microbial infections.
  • Conducted in-vitro and in-vivo experiments
  • Administered methanolic root extracts at 500 mg/kg
  • Measured serum blood glucose, cholesterol levels, and antimicrobial activity against specific bacteria
  • Extracts significantly lowered blood glucose levels (p < 0.001)
  • Noticeable reduction in LDL-C and total cholesterol levels (p < 0.001)
  • Increased HDL-C levels (p < 0.01)
  • Demonstrated antimicrobial activity against Staphylococcus aureus and Aspergillus niger (p < 0.001)
  • Inhibited Escherichia coli growth significantly (p < 0.01)

Cite This Study

Santo et al. (2024) studied this question.

synapsesocial.com/papers/69a3d830ec16d51705d2ee26https://doi.org/10.57647/tpr.2025.0903.15
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