Demonstrates how monocytic myeloid-derived suppressor cells impact allograft rejection in liver transplantation, suggesting new therapeutic strategies.
Liver transplant rejection significantly affects patient prognosis. Myeloid-derived suppressor cells (MDSCs), known for their potent immunoregulatory functions, represent a promising target for managing liver transplant rejection. This study aimed to systematically characterize the diversity of MDSC subsets and their context-dependent functions, particularly within the context of transplant tolerance.
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Zhou et al. (2026) studied this question.
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