Target trial emulation finds fentanyl use raises delirium incidence in cardiac surgery patients, indicating potential risks.
The findings of this study, conducted within a TTE framework, indicate that the utilization of fentanyl for pain management during the initial 24 h following cardiac surgery is associated with a higher incidence and earlier onset of postoperative delirium compared to morphine.
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Qu et al. (2026) studied this question.
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