Why the study?
What is the incidence of delayed respiratory depression following high-dose fentanyl anesthesia in patients undergoing aortocoronary artery bypass?
What is the incidence of delayed respiratory depression following high-dose fentanyl anesthesia in patients undergoing aortocoronary artery bypass?
High-dose fentanyl anesthesia during cardiac surgery can cause life-threatening delayed respiratory depression 2 to 6 hours postoperatively, which is reversible with naloxone or muscle relaxants.
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May warrant extended monitoring after high-dose fentanyl; leaves open incidence, risk factors, and need for prospective validation.
Caspi et al. (1988) studied this question.
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