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October 27, 2015Journal of the American Heart AssociationOpen Access

Incidence of Venous Thromboembolism and Benefits and Risks of Thromboprophylaxis After Cardiac Surgery: A Systematic Review and Meta‐Analysis

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Why the study?

Does pharmacological VTE prophylaxis reduce venous thromboembolism in patients after cardiac surgery?

Population

Patients after cardiac surgery who have no active bleeding

Design

Meta-analysis

Authors

KHKwok M. HoEBEbrahim BhamWPWarren Pavey

Discussion

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Overview

Supports immediate post-cardiac surgery VTE prophylaxis without bleeding; confirms efficacy via Level 1 meta-analysis.

Structured PICO

Does pharmacological VTE prophylaxis reduce venous thromboembolism in patients after cardiac surgery?

P
Population
Patients after cardiac surgery who have no active bleeding
I
Intervention
Pharmacological VTE prophylaxis initiated as soon as possible
O
Outcome
Incidence of Venous Thromboembolismhard clinical

Initiating pharmacological VTE prophylaxis as soon as possible after cardiac surgery is highly recommended for patients without active bleeding.

Cite This Study

Ho et al. (2015) studied this question.

synapsesocial.com/papers/69a499df5cb19ed11668c8dahttps://doi.org/10.1161/jaha.115.002652
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1NICE thromboprophylaxis guidelines are not associated with increased pericardial effusion after surgery of the proximal thoracic aorta2013 · 4 citations
  2. 2Incidence and Prevention of Pulmonary Embolism After Coronary Artery Surgery1975 · 26 citations
  3. 3Low Molecular Weight Heparin After Mechanical Heart Valve Replacement2000 · 153 citations
  4. 4Coronary artery bypass surgery in patients over age 70 years: Report from the milwaukee cardiovascular data registry1987 · 27 citations
  5. 5A continuous heparin infusion does not prevent catheter-related thrombosis in infants post cardiac surgery2010 · 56 citations