Two Cases of Simultaneous Breast Reconstruction and Risk-Reducing Salpingo-Oophorectomy in Patients with Hereditary Breast and Ovarian Cancer Syndrome

Breast cancer is the most common malignancy among women, with a lifetime risk of more than 10%. Hereditary breast and ovarian cancer syndrome (HBOC) is an autosomal dominant disorder characterized by pathogenic variants in the BRCA1/2 genes. HBOC dramatically increases the risk of breast and ovarian cancers. After the inclusion of BRCA testing and risk-reducing surgeries (mastectomy with reconstruction and salpingo-oophorectomy) in health insurance coverage in April 2020, it is expected that more patients will be diagnosed with HBOC and require treatment. Given the prophylactic nature of these procedures, there is a high demand for breast reconstruction, making the role of plastic surgeons crucial. Given patients with HBOC frequently require multiple operations, a multidisciplinary approach involving combined surgical procedures can significantly reduce the number of interventions, offering substantial physical and psychological benefits. Here, we present our experience with a combined procedure performed with the gynecology department, comparing it with traditional surgical approaches and addressing the challenges encountered.