Reports adverse effects of obesity and dysglycemia on bone quality in youth, suggesting sex-related differences.
There is a negative relationship between adiposity and insulin resistance with bone microarchitecture and strength in youth after accounting for age, sex, height and lean mass. There appears to be sexual dimorphism in these relationships, with more negative effect of adiposity and dysglycemia on bone quality in males.
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Bacha et al. (2026) studied this question.
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