Observational study reveals skeletal differences during puberty in adolescents with type 1 diabetes, suggesting critical intervention periods.
T1D exerts sex- and pubertal stage-specific skeletal effects. Mid-pubertal boys show trabecular and cortical deficits with reduced strength, whereas early-pubertal girls show no deficits. Mid-puberty in boys represents a critical window for skeletal vulnerability and potential intervention.
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Brossfield et al. (2026) studied this question.
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