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Summarizes the existing research on sudden unexpected death in epilepsy (SUDEP) to improve understanding and prevention.

Translational Research Symposium: Current State of SUDEP Research

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This review summarizes current findings on SUDEP, highlighted by genetic, physiological, and technological aspects in epilepsy.

Summarizes the existing research on sudden unexpected death in epilepsy (SUDEP) to improve understanding and prevention.
Reviews human cohort studies on SUDEP incidence.
Explores genetic and cardio-respiratory risk factors.
Assesses animal models used in SUDEP research.
Investigates EEG biomarkers during sleep.
Considers wearable devices designed to monitor risk.
People with epilepsy face a significantly higher risk of SUDEP than the general population.
Some drug-resistant epilepsies have SUDEP rates exceeding 9:1000 person-years.
Identified factors include genetic predispositions and cardio-respiratory issues.
Wearable devices may offer promising methods to reduce SUDEP risk.

Ryan et al. (2026) studied this question.

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