What does this research mean for the field?

Maternal supplementation with Lactobacillus reuteri SGL 01 does not modify breast milk microbiota but increases beneficial gut bacteria in neonates. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the effects of maternal L. reuteri SGL 01 supplementation on breast milk and neonatal gut microbiota.

March 2, 2026Open Access

Effect of Supplementation with Lactobacillus reuteri SGL 01 in Lactating Women on Breast Milk and Neonatal Gut Microbiota: An Exploratory, Randomized, Open-Label Clinical Trial

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To evaluate the effects of maternal L. reuteri SGL 01 supplementation on breast milk and neonatal gut microbiota.
Randomized, open-label clinical trial
27 lactating mothers and their infants participated
Mothers received daily L. reuteri SGL 01 or no supplementation for 30 days
Microbial composition assessed using quantitative real-time PCR
No significant changes in breast milk microbiota observed
Neonatal feces from the supplemented group showed significant increases in Bifidobacterium spp. and Lactobacillus spp.
Clostridium spp. also increased significantly in the neonates
Control group showed slight reduction in Clostridium spp.

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Implication

Exploratory clinical trial evaluates impacts of L. reuteri SGL 01 supplementation on infant gut microbiota, indicating potential benefits.

Cite This Study

Pagliarini et al. (2026) studied this question.

synapsesocial.com/papers/69a52e56f1e85e5c73bf1fb9 https://doi.org/10.3390/nu18050794

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Implication

Exploratory clinical trial evaluates impacts of L. reuteri SGL 01 supplementation on infant gut microbiota, indicating potential benefits.

Effect of Supplementation with Lactobacillus reuteri SGL 01 in Lactating Women on Breast Milk and Neonatal Gut Microbiota: An Exploratory, Randomized, Open-Label Clinical Trial

Key Points

Discussion

Implication

Cite This Study

Effect of Supplementation with Lactobacillus reuteri SGL 01 in Lactating Women on Breast Milk and Neonatal Gut Microbiota: An Exploratory, Randomized, Open-Label Clinical Trial

Key Points

Discussion

Implication

Cite This Study

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