What type of study is this?

This is a Validation Study study.

What question did this study set out to answer?

To evaluate the effects of Lactobacillus reuteri LMG-P 27481 on gut microbiota diversity and function.

November 20, 2025BiomedicinesOpen Access

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To evaluate the effects of Lactobacillus reuteri LMG-P 27481 on gut microbiota diversity and function.
Interventional open-label study
Conducted on 20 healthy adults
Probiotic administered as Reuterin® LMG for 28 days
Microbiota analysis at three time points: enrollment, end of supplementation, and follow-up
Gastrointestinal symptoms assessed using the GSRS
Observed variations in gut microbiota composition and functionality
Improvement in intestinal permeability and barrier effect
Increase in short-chain fatty acids
Probiotic was safe and effective in reducing symptoms

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Pilot study shows probiotics improve gut microbiota diversity and intestinal permeability in healthy adults, indicating potential health benefits.

Ojetti et al. (2025) studied this question.

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Pilot study shows probiotics improve gut microbiota diversity and intestinal permeability in healthy adults, indicating potential health benefits.