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March 3, 2026Discover MedicineOpen Access

The performance of the current and emerging tuberculosis diagnostic test and the potential of DNA aptamer-based point-of-care biosensor: a review

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Authors

RRResmond L. ReañoUniversity of the Philippines Los Baños

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Implication

This review uncovers the potential of DNA aptamer biosensors as alternatives to existing tuberculosis diagnostics in low-income countries, suggesting improved outcomes.

Key Points

This review aims to evaluate the performance of current and emerging tuberculosis diagnostic tests, focusing on DNA aptamer-based biosensors.
Reviewed literature from multiple databases for relevant tuberculosis diagnostics and aptamer testing studies.
Selected articles reporting on sensitivity and selectivity of aptamer-based POC biosensors.
Ranked current TB diagnostics based on the WHO 'ASSURED' criteria.
Aptamers improved performance across various TB bioassays.
The lateral flow device was the top performer among commercially available TB tests.
Electrochemical biosensors and miniaturized surface plasmon resonance show promise for future development.

Cite This Study

Resmond L. Reaño (2026) studied this question.

synapsesocial.com/papers/69a67dd6f353c071a6f09e59 https://doi.org/10.1007/s44337-026-00562-3

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Implication

This review uncovers the potential of DNA aptamer biosensors as alternatives to existing tuberculosis diagnostics in low-income countries, suggesting improved outcomes.

The performance of the current and emerging tuberculosis diagnostic test and the potential of DNA aptamer-based point-of-care biosensor: a review

Discussion

Member takes

Implication

Key Points

Cite This Study

The performance of the current and emerging tuberculosis diagnostic test and the potential of DNA aptamer-based point-of-care biosensor: a review

Discussion

Member takes

Implication

Key Points

Cite This Study

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