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March 3, 2026Open Access

Biomarkers in Colorectal Cancer: Clinically Relevant Diagnostic and Prognostic Molecular Features, and the Future of Precision Medicine

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Authors

RWRebecca WhitmerJSJulia SepulvedaJGJason Gandhi

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Overview

This review explores biomarkers affecting diagnosis and treatment in colorectal cancer, highlighting their implications for precision medicine.

Key Points

  • The aim is to understand the molecular features of colorectal cancer biomarkers and their relevance for diagnosis and treatment.
  • Reviewed genetic and epigenetic alterations in colorectal cancer.
  • Analyzed specific gene mutations and their implications on tumor biology.
  • Explored the prevalence and prognostic significance of identified biomarkers.
  • Identified key mutations like MMR deficiency and high microsatellite instability.
  • Highlighted common mutations in CRC, such as APC, TP53, and KRAS.
  • Demonstrated how biomarker-driven strategies impact CRC management.

Cite This Study

Whitmer et al. (2026) studied this question.

synapsesocial.com/papers/69a67f06f353c071a6f0ac98https://doi.org/10.3390/jpm16030132
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