Key result
VRA in athletes with normal echo is linked to ~53% developing heart disease, driven by persistence.
Why the study?
Ventricular repolarization abnormalities represent a grey area in athlete screening, prompting this study to clarify their natural history and factors associated with structural cardiovascular diagnosis.
Does the persistence of ventricular repolarization abnormalities predict future cardiovascular diagnoses in athletes with normal baseline echocardiography?
Does the persistence of ventricular repolarization abnormalities predict future cardiovascular diagnoses in athletes with normal baseline echocardiography?
In athletes with ventricular repolarization abnormalities and normal baseline echocardiography, prolonged surveillance is warranted as over half eventually receive a structural cardiovascular diagnosis, particularly those with persistent resting abnormalities.
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May warrant prolonged surveillance for athletes with persistent ventricular repolarization abnormalities; extends evidence linking persistence to structural heart disease.
Bianco et al. (2026) studied this question. Among athletes with ventricular repolarization abnormalities and normal echocardiography, 52.8% were diagnosed with heart disease over 7.3 years, with resting VRA persistence linked to diagnosis (p=0.
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