Sex Differences in Prehospital Delays in Patients With ST‐Segment–Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Why the study?
Women with STEMI experience reperfusion delays compared with men, but data on specific time components from symptom onset to reperfusion are limited.
Does female sex increase prehospital and hospital delays in patients with STEMI undergoing PCI?
Population
6330 patients with STEMI treated with PCI and transported by EMS across 30 hospitals
Comparison
Women vs men
Design
Registry-based linkage cohort study
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
Longer STEMI delays in women were associated with higher mortality; leaves open whether targeted protocols improve equity.
Structured PICO
Does female sex increase prehospital and hospital delays in patients with STEMI undergoing PCI?
P
Population
6,330 patients with ST-segment-elevation myocardial infarction (STEMI) transported by emergency medical services (EMS) and treated with percutaneous coronary intervention (PCI), 21% women.
I
Intervention
Female sex
C
Comparator
Male sex
O
Outcome
EMS call-to-door time (prehospital system delay)
Women with STEMI experience significantly longer prehospital and hospital delays for reperfusion therapy, which is associated with higher 30-day mortality and major bleeding compared to men.
Cite This Study
Stehli et al. (2021) studied this question.