Why the study?
Higher doses of anthracyclines and heart-relevant radiotherapy increase cardiovascular disease risk, motivating an assessment of cardiovascular disease, risk factors, and lifestyle behaviors across cardiotoxic treatment risk groups.
Do cardiovascular disease prevalence, CVD risk factors, and lifestyle behaviors differ across cardiotoxic treatment risk groups in adult childhood cancer survivors?
Population
356 adult childhood cancer survivors aged ≥18 years diagnosed at ages 0-20 surviving ≥5 years
Comparison
Cardiotoxic treatment risk groups: no/low risk vs moderate risk vs high risk
Design
Cross-sectional study
Authors
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Warrants universal cardiovascular health promotion in all childhood cancer survivors; challenges cardiotoxic treatment-based risk stratification.
Do cardiovascular disease prevalence, CVD risk factors, and lifestyle behaviors differ across cardiotoxic treatment risk groups in adult childhood cancer survivors?
Adult childhood cancer survivors have a high prevalence of CVD risk factors and poor adherence to lifestyle recommendations regardless of their prior cardiotoxic treatment risk, highlighting the need for universal cardiovascular health promotion in this population.
Li et al. (2026) studied this question.
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