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March 3, 2026Frontiers in Aging3 citationsOpen Access

Periorbital skin index as a biomarker for biological aging and health status

KGKi-Nam GuSLSangseob LeemHKHanji Kim

Key Points

  • Periorbital skin age is identified as a non-invasive biomarker reflecting skin aging and health status.
  • The analysis shows that skin assessment in the eye area can indicate underlying medical conditions and aging.
  • Assessment using clinical evaluations indicates promising results for eye-region skin assessment as an aging marker.
  • The findings support a practical tool for health monitoring, which may improve disease risk evaluation procedures.

Abstract

This study establishes 'periorbital skin age' as a non-invasive biomarker that effectively reflects both the progression of skin aging and underlying medical conditions. Our findings highlight the potential utility of eye-region skin assessment in clinical and health monitoring settings, offering a practical tool for evaluating physiological aging and disease risk.

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Cite This Study

Gu et al. (2026) studied this question.

synapsesocial.com/papers/69a75c2ac6e9836116a24b9bhttps://doi.org/10.3389/fragi.2026.1715245
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