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February 3, 2026Chromatographia

Insight into the Retention Behaviours of Proton Pump Inhibitor Drugs Using Homemade ZIC-HILIC Columns with Greenness, Whiteness, and Blueness Evaluation

Mustafa J. Mohammed Ashraf Saad Rasheed Bashar Qasim

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Key Points

Retention behaviour of proton pump inhibitors is influenced by specific homemade ZIC-HILIC columns, emphasizing the importance of design.
The evaluation of greenness, whiteness, and blueness metrics shows significant differences in retention patterns and properties of these drugs.
The method employed synthesizes custom ZIC-HILIC columns that enhance the understanding of how proton pump inhibitors are retained during analysis.
Further validation of these metrics in various settings may enhance analytical applications of proton pump inhibitors, indicating broader relevance.

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Implication

Analysis explores the retention behaviours of proton pump inhibitors using homemade ZIC-HILIC columns, suggesting practical evaluation methods.

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Cite This Study

Mohammed et al. (2026) studied this question.

synapsesocial.com/papers/69a7608ac6e9836116a2d61c https://doi.org/10.1007/s10337-026-04478-z

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Use of proton pump inhibitors in adults in France: a nationwide drug utilization studyOriginal Research · 2019 · 136 citations
2Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppressionReview · 2016 · 468 citations
3Intermittent vs Continuous Proton Pump Inhibitor Therapy for High-Risk Bleeding UlcersSystematic Review · 2014 · 161 citations
4Awareness, attitude and behavior regarding proton pump inhibitor among medical staff in the Southwest of ChinaCross-Sectional Study · 2019 · 46 citations
5A Sensitive HPLC–MS/MS Method for Determination of Obeticholic Acid in Human Plasma: Application to a Pharmacokinetic Study in Healthy VolunteersOriginal Research · 2021 · 2 citations

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