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March 3, 2026Journal of Pediatric and Adolescent Gynecology0 citations

Efficacy and tolerability of elagolix in adolescents and young adults with endometriosis: a small, single-center retrospective cohort study

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JSJessica Y. ShimASAva ScatoniMLMarc R. Laufer

Key Points

  • Elagolix demonstrates significant efficacy for treating endometriosis-related symptoms in adolescents and young adults.
  • Key metrics indicate that elagolix improved pain levels by more than 50% over a 3-month period.
  • Retrospective cohort analysis utilized medical records from a single center over several years.
  • Highlighting the need for additional studies on long-term effects and larger sample sizes.
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Cite This Study

Shim et al. (2026) studied this question.

synapsesocial.com/papers/69a76165c6e9836116a2f463https://doi.org/10.1016/j.jpag.2026.02.008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist2017 · 501 citations
  2. 2Long-term safety and efficacy of elagolix treatment in women with endometriosis-associated pain: primary results from two phase 3 extension studies2017 · 4 citations
  3. 3Revised American Society for Reproductive Medicine classification of endometriosis: 19961997 · 3,029 citations
  4. 4Treatment of Adolescent Endometriosis Before, During, and After Use of Gonadotropin-Releasing Hormone Agonists: A Retrospective Cohort Study2023 · 6 citations
  5. 5Clinical Pharmacology of Elagolix: An Oral Gonadotropin-Releasing Hormone Receptor Antagonist for Endometriosis2019 · 68 citations