Key result
Smaller right ventricular volume links to worse exercise performance in young repaired tetralogy of Fallot patients.
Why the study?
Is a smaller right ventricle associated with poorer exercise performance in young patients with repaired tetralogy of Fallot?
Cross-Sectional (n=37)
No
Is a smaller right ventricle associated with poorer exercise performance in young patients with repaired tetralogy of Fallot?
p-value: p=0.0004
In young patients with repaired tetralogy of Fallot, a smaller right ventricle correlates with worse exercise performance, suggesting that exercise intolerance can be independent of severe RV dilatation.
Smaller RV was associated with worse exercise performance in young rTOF; hypothesis-generating and should not yet change practice.
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Mhanna et al. (2026) conducted a cross-sectional in Repaired Tetralogy of Fallot (rTOF) (n=37). Right ventricular size (RVEDVi) vs. Larger right ventricular size was evaluated on Correlation between body surface area-indexed right ventricular end-diastolic volume (RVEDVi) and peak oxygen pulse (pOP/BSA) (p=0.0004). A smaller right ventricle was significantly associated with worse exercise performance, indicating that exercise intolerance can be independent of right ventricular dilatation in young patients with repaired tetralogy of Fallot.
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