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February 5, 2026Spectrochimica Acta Part B Atomic Spectroscopy

Inductively coupled plasma – mass spectrometry to evaluate the impact of long-term Zn supplementation in liver tissue of APP/PS1 mouse model of Alzheimer's disease

Marta Marina-Latorre Lara Lobo Enol Artime Rosario Pereiro

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Key Points

Long-term zinc supplementation impacts liver tissue in the APP/PS1 mouse model for Alzheimer's disease.
Findings indicate significant changes in liver biomarker levels due to zinc treatment, notably with mass spectrometry techniques.
Assessment using inductively coupled plasma mass spectrometry highlights molecular changes linked to zinc exposure in the model.
Results may enable further exploration of zinc’s role in Alzheimer’s pathology and potential therapeutic avenues.

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Implication

Observational analysis reveals long-term zinc supplementation affects liver tissue in APP/PS1 mice, suggesting a potential link to Alzheimer’s.

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Cite This Study

Marina-Latorre et al. (2026) studied this question.

synapsesocial.com/papers/69a7673ebadf0bb9e87e0260 https://doi.org/10.1016/j.sab.2026.107466

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