Key result
Metabolic syndrome and obesity metrics link to high Framingham Risk Scores, especially in obese women.
Why the study?
The study was conducted to analyze the impact of obesity and metabolic syndrome on cardiovascular risk and cardiac conditions in individuals with obesity with and without metabolic syndrome.
Does the presence of metabolic syndrome affect cardiovascular risk (Framingham Risk Score) in obese adults?
Does the presence of metabolic syndrome affect cardiovascular risk (Framingham Risk Score) in obese adults?
Obese individuals both with and without metabolic syndrome exhibit high cardiovascular risk, particularly women, emphasizing the need for cardiovascular risk management in all obese patients.
Supports CV risk management in all obese patients independent of metabolic syndrome; extends evidence especially in women.
Background: To analyze the impact of obesity and MS on cardiovascular risk and cardiac conditions with obesity with and without MS. Methods: The study conducted was a descriptive retrospective cross-sectional study, carried out with obese patients under care at the Cardiology Outpatient Clinic of João Barros Barreto University Hospital in Belém/PA. Inclusion criteria included individuals over 18 years old, diagnosed with obesity with or without Metabolic Syndrome, and who had updated laboratory, electrocardiographic, and echocardiographic exams available. The study was conducted in 2023 and is part of the project approved under opinion No. 69722423.30000.0018. The Chi-square test was used to describe the relationship between variables, with statistically significant values considered as hypothesis tests with p <0.05. Results: The study evaluated 100 individuals with obesity, of which 60 had MS, with a mean age of 54 years and a prevalence of females. There was an association between the presence of high Framingham Risk Score (FRS) and changes in BMI, waist circumference, systolic blood pressure (SBP), HDL, triglycerides, total cholesterol, and glucose indices for both groups. There was an association between the presence of MS and high FRS in women. Conclusion: Thus, in both groups, there was a occurrence of high FRS, especially in obese women. Obese individuals without MS have a similar risk, requiring appropriate attention to the cardiac health of such individuals.
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Luz et al. (2025) studied this question. High Framingham Risk Score was significantly associated with obesity-related metrics and metabolic syndrome, especially in obese women, indicating elevated cardiovascular risk.
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