What question did this study set out to answer?

This study aims to compare the effectiveness and safety of radiotherapy versus interventional therapy in treating adrenal oligometastases.

March 4, 2026Journal of Clinical Oncology

Comparative outcomes of radiotherapy and interventional therapy for adrenal oligometastases: A multicenter retrospective study.

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Authors

YZYanke ZhangFuyang Normal University LXLin XieFoshan University XCXianda ChenSun Yat-sen University

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Implication

Retrospective study compares radiotherapy and interventional therapy outcomes in adrenal oligometastases, suggesting similar efficacy and safety profiles.

Key Points

This study aims to compare the effectiveness and safety of radiotherapy versus interventional therapy in treating adrenal oligometastases.
Multicenter retrospective comparison of 245 patients with adrenal metastases (2008–2024)
Primary endpoint was overall survival; secondary endpoint was local progression-free survival
Utilized IPTW-adjusted Cox analysis to balance covariates
Compared outcomes and toxicity using weighted models
Local recurrence rates: 17.3% (radiotherapy) vs 22.0% (interventional therapy)
Death rates: 44.9% (radiotherapy) vs 70.3% (interventional therapy)
Adjusted overall survival and local progression-free survival Harris ratios indicated no significant differences
Lung primaries and larger lesions (greater than 42 mm) predicted poorer overall survival

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd1dd48f933b5eed923b https://doi.org/10.1200/jco.2026.44.7_suppl.1

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Implication

Retrospective study compares radiotherapy and interventional therapy outcomes in adrenal oligometastases, suggesting similar efficacy and safety profiles.

Comparative outcomes of radiotherapy and interventional therapy for adrenal oligometastases: A multicenter retrospective study.

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparative outcomes of radiotherapy and interventional therapy for adrenal oligometastases: A multicenter retrospective study.

Discussion

Member takes

Implication

Key Points

Cite This Study

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