Key result
Poor neighborhood and lifecourse socioeconomic exposures linked to higher CVD, CKD, and dementia burden.
Population
15,792 men and women recruited from four geographically distinct United States communities
Design
Review article summarizing community surveillance and longitudinal cohort data
Authors
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May warrant SDOH assessment in CV risk stratification; reinforces ARIC evidence on lifecourse neighborhood effects.**[[1]](https://www.ahajournals.org/doi/10.1161/cir.0000000000000228)[[2]](https://www.jacc.org/doi/10.1016/j.jacc.2021.04.
The ARIC study provides extensive evidence that social determinants of health, including neighborhood deprivation and socioeconomic status across the lifecourse, significantly impact cardiovascular disease risk and outcomes.
Kucharska-Newton et al. (2026) studied this question. Poor neighborhood socioeconomic status and lifecourse socioeconomic exposures significantly increase the burden of cardiovascular disease, dementia, and kidney disease in ARIC participants.
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