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This overview explores the role of estrogen and hormone replacement therapy in skin health during aging.

March 4, 2026LifeOpen Access

Overview of Aging, Skin Health, Estrogen, Menopause and HRT

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This overview examines the effects of hormone replacement therapy on skin health in aging women, suggesting its renewed relevance.

This overview explores the role of estrogen and hormone replacement therapy in skin health during aging.
Review of historical and recent studies on HRT and skin health.
Analysis of the Women’s Health Initiative findings and their impact on HRT perception.
Discussion of the timing hypothesis related to HRT interventions.
HRT may positively impact skin parameters based on a recent systematic review and meta-analysis.
The FDA's removal of misleading HRT warnings highlights the importance of estrogen for women's health.
Exploration of HRT benefits not only for symptomatic women but also for aesthetic improvements.

Lephart et al. (2026) studied this question.

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