What question did this study set out to answer?

To assess the effects of depression and anxiety on survival outcomes in individuals with gastric and esophageal cancer.

March 5, 20260 citations

Effects of Depression and Anxiety on Survival Prognosis Among Individuals With Gastric and/or Esophageal Cancer: Systematic Review and Meta-Analysis.

RBReza Bayati SQShohra Qaderi MPMohammad Hossein Panahi

Key Points

To assess the effects of depression and anxiety on survival outcomes in individuals with gastric and esophageal cancer.
Conducted a systematic review and meta-analysis of existing studies on mental health and cancer survival.
Analyzed data on depression and anxiety levels in cancer patients.
Evaluated survival rates and prognosis related to psychological distress.
Depression and anxiety are associated with lower survival rates in esophagogastric cancer patients.
Psychological distress significantly predicts poorer prognosis in this population.
The need for standardized mental health assessments and interventions is highlighted.

Abstract

Depression and anxiety appear to predict poorer survival in esophagogastric cancer patients, underscoring the prognostic importance of psychological distress. Future prospective studies with standardized, longitudinal assessments of mental health and interventional trials are needed to clarify causal pathways and test whether psychological support can improve survival and quality of life in this vulnerable population.

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