In vitro evaluation demonstrates that Triton maintains dentin integrity with and without laser activation, indicating its potential in endodontic procedures.
Background: Complete disinfection of the root canal while preserving dentinal integrity remains a major challenge. Diode laser activation improves irrigant penetration yet its combined effect with novel irrigants Triton and Twin Kleen on dentin composition remains unclear. Aims: To compare the effect of Triton, Twin Kleen, and sodium hypochlorite (5.25% NaOCl) +ethylenediaminetetraacetic acid (17% EDTA) with and without diode laser activation on the radicular dentin composition. Materials and Methods: Eighty extracted human mandibular premolars were prepared and divided into four groups ( n = 20): Normal saline, Triton, Twin Kleen, and NaOCl + EDTA. Each group was further subdivided into diode laser-activated and nonactivated subgroups. Longitudinal dentin sections were analyzed using attenuated total reflectance Fourier-transform infrared spectroscopy to assess the root dentin inorganic and organic alterations. Statistical Analysis: Kruskal–Wallis and Mann–Whitney U tests ( P < 0.05). Results: Among both laser and nonlaser activated groups, normal saline preserved the highest carbonate and amide peaks, followed by Triton and Twin Kleen and least in NaOCl + EDTA. Diode laser activation slightly decreased all FTIR ratios. Conclusion: Triton activated with and without diode laser, maintained dentin composition effectively, supporting its use as a single step irrigant in endodontic therapy.
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Halkai et al. (2026) studied this question.
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