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May 22, 2026BMC Oral HealthOpen Access

Dentinal tubule penetration of sodium hypochlorite and super-oxidized water using diode laser and passive ultrasonic activation: an in vitro confocal laser scanning microscopy study

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Authors

PHPalak HiraniMCManoj ChandakAPAditya Patel

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Overview

In vitro study demonstrates increased penetration of irrigants in teeth using activation methods, highlighting implications for root canal treatment.

Key Points

  • This study aims to compare the penetration of sodium hypochlorite and super-oxidized water into dentinal tubules when activated by diode laser and ultrasonic methods.
  • In vitro study using 60 extracted human single-rooted teeth.
  • Teeth randomly allocated to six groups based on irrigant type and activation method.
  • Penetration measured using confocal laser scanning microscopy after standardized preparation and irrigation.
  • Activated irrigation methods significantly increased dentinal tubule penetration compared to conventional needle irrigation.
  • Diode laser activation achieved the highest penetration, followed by passive ultrasonic activation and conventional irrigation.
  • Super-oxidized water showed penetration similar to sodium hypochlorite under activated conditions.

Cite This Study

Hirani et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff33bd674f7c03778bb56https://doi.org/10.1186/s12903-026-08649-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of different activation procedures on sodium hypochlorite penetration into dentinal tubules after endodontic retreatment via confocal laser scanning microscopy2024 · 4 citations
  2. 2Influence of passive ultrasonic irrigation cycles on the penetration depth of sodium hypochlorite into root dentin2025
  3. 3Dentinal tubule penetration of sodium hypochlorite in root canals with and without mechanical preparation and different irrigant activation methods2022 · 9 citations
  4. 4Antimicrobial efficacy of superoxide water as an intracanal irrigant in primary anterior teeth against facultative anaerobes: A randomized clinical trial2023 · 1 citations
  5. 5Efficacy of Laser-Activated Irrigation Versus Ultrasonic-Activated Irrigation: A Systematic Review2023 · 27 citations