Three components synthesis of tetracyclic fused Scafold of Pyrazolopyrimidobenzosultam derivatives

A feasible and effective method for synthesising Pyrazolopyrimidobenzosultam by a three-component one-pot reaction comprising N -methyl 1,2-benzothiazinone 1,1-dioxide, a suitable benzaldehyde, and 5-amino pyrazole with KOH has been presented. This method was implemented successfully without the use of heavy metals and had positive yields. Development of a new heterocyclic structure incorporating pyrazole, dihydropyridine and sultam scaffolds through Michael addition, cyclisation, and condensation processes.