Observational analysis supports the role of digital rectal examination in advanced prostate cancer, suggesting its ongoing relevance alongside advanced imaging.
Despite the rise of advanced imaging techniques, DRE remains a valuable adjunctive tool in identifying high-risk and advanced PCa. When interpreted alongside mpMRI and PSMA PET/CT findings, DRE provides additional clinical insight, supporting its continued role in risk stratification rather than screening in the modern diagnostic workflow.
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Eker et al. (2026) studied this question.
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