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Diagnostic role of maternal serum prokineticin-1 indicates adverse outcomes in pregnancies affected by preeclampsia, suggesting its use in prediction models.
Maternal serum PROK-1 was elevated in PE and correlated with disease severity and adverse perinatal outcomes. Although inadequate as a stand-alone marker, PROK-1 may complement existing angiogenic biomarkers in multimarker prediction models.
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Özkan et al. (2026) studied this question.
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