Diagnostic and prognostic role of maternal serum prokineticin-1 in preeclampsia and adverse pregnancy outcomes

Key Points

• This research aims to evaluate the role of maternal serum prokineticin-1 as a diagnostic and prognostic marker in preeclampsia.
• Examined levels of maternal serum PROK-1 in pregnancies with preeclampsia
• Coronelated PROK-1 levels with disease severity and perinatal outcomes
• Compared PROK-1 with existing angiogenic biomarkers.
• Elevated PROK-1 levels were observed in women with preeclampsia
• The severity of preeclampsia correlated with higher PROK-1 levels
• PROK-1 may enhance the predictive accuracy of multimarker models for adverse pregnancy outcomes.