Why the study?
Preeclampsia is a major cause of maternal morbidity and mortality, prompting investigation into whether serum levels of HIF-1A, VEGF, IP-10, and MMP-13 correlate with disease severity to identify predictors for preeclampsia.
Do serum biomarkers (HIF-1A, VEGF, IP-10, MMP-13) accurately diagnose and predict the severity of preeclampsia in pregnant women?
Do serum biomarkers (HIF-1A, VEGF, IP-10, MMP-13) accurately diagnose and predict the severity of preeclampsia in pregnant women?
Serum concentrations of MMP-13 and VEGF may serve as useful biomarkers for diagnosing and monitoring the severity of preeclampsia.
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Serum MMP-13 and VEGF may aid severe preeclampsia identification; leaves open routine predictive use pending prospective validation.
Dijmărescu et al. (2022) studied this question.
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