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This study aims to examine the histological and biochemical development of the pars distalis in chick embryos.

March 6, 2026Open Access

A histological and histochemical study of the development of the pituitary gland with particular emphasis on the pars distalis in chick embryos

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A histological analysis tracks pituitary gland development in chick embryos, suggesting key hormone production timelines.

This study aims to examine the histological and biochemical development of the pars distalis in chick embryos.
Investigated chick embryos from the 3rd day of incubation to one week posthatching.
Analyzed staining patterns for various secretory granules.
Identified different cell types and their potential hormone productions.
Secretory granules at the apical portion of luminal cells tested positive for multiple biochemical markers.
Beta and delta cells first appeared at 7 days, with beta cells likely producing thyroid-stimulating hormone.
Cephalic acidophil cells emerged at 11 days, while caudal acidophil cells appeared at 15 days, indicating hormone production timelines.

Lynn Elizabeth Levy (1971) studied this question.

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