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This study investigates how exogenous insulin affects the development of pancreatic islets in chick embryos.

March 6, 2026Open Access

A histological study of the development of the pancreas, with particular emphasis on the islets of Langerhans, in insulin treated chick embryos

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Histological study examines pancreatic islet development in chick embryos treated with insulin, indicating hormonal influence on growth.

This study investigates how exogenous insulin affects the development of pancreatic islets in chick embryos.
Histological and histochemical analysis of pancreas development
Exogenous insulin treatment of chick embryos during incubation
Comparison of insulin-treated and control tissues
Use of electron microscopy to confirm findings
Insulin treatment delayed initial formation of beta islets
Later, insulin treatment increased endogenous insulin production
Insulin boosted activity of alpha cells and glucagon production
Early insulin treatment reduced ribonucleic acid content in pancreatic cells
Glycogen storage patterns were altered, with increases in alpha and acinar cells

Rajdeo Kalliecharan (1971) studied this question.

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