PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 6, 2026Analytical Methods0 citations

A fluorogenic and ultrabright probe for imaging of lipid droplets in live and fixed cells

GZGuorui ZhaoGJGuanchang JiDSDongdong Song

Key Points

  • This research aims to develop a new fluorescent probe to specifically image lipid droplets in both live and fixed cells.
  • Developed a novel fluorescent probe, TPE-Q, for targeting lipid droplets.
  • Tested the probe’s effectiveness in live and fixed cell environments.
  • Assessed interactivity of the probe with lipid droplets under various conditions.
  • The new probe showed strong fluorescence specific to lipid droplets.
  • Demonstrated successful imaging in both living and fixed cell systems.
  • Enabled clearer observation of lipid droplets compared to existing methods.

Abstract

Lipid droplets(LDs) play an vital role in energy homeostasis and cellular signaling. Therefore, the visualization of LDs is very important. To this end, a new LD-specific fluorescent probe, TPE-Q, was...

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/69aa7066531e4c4a9ff5a258https://doi.org/10.1039/d6ay00188b
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole2001 · 8,338 citations
  2. 2A role for lipid droplets in inter‐membrane lipid traffic2009 · 285 citations
  3. 3Adding fuel to the fire: The lipid droplet and its associated proteins in cancer progression2022 · 39 citations
  4. 4A TICT-AIE activated dual-channel fluorescence-on probe to reveal the dynamics mechanosensing of lipid droplets during ferroptosis2024 · 17 citations
  5. 5The macrophage STING-YAP axis controls hepatic steatosis by promoting the autophagic degradation of lipid droplets2023 · 52 citations