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Demonstrates that nano-piperine improves immune function in male rats, suggesting a potential supplement during glucocorticoid therapy.
Nano-piperine and vitamin C mitigated dexamethasone-induced immunosuppression by increasing WBC counts, modulating leukocyte differentiation, reducing inflammation (IL-6), and maintaining the integrity of lymphoid tissue. These compounds demonstrate potential as supplementary treatments to reduce immune toxicity associated with glucocorticoids.
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Alsaad et al. (2026) studied this question.
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