Treatment Strategy for Refractory Dissecting Cellulitis of the Scalp Using Bimekizumab, Isotretinoin, and Oral Antibiotics

Dissecting cellulitis of the scalp (DCS) is a chronic inflammatory disorder of the scalp that manifests as inflamed nodules and abscesses, with subsequent patchy, scarring hair loss. While its exact pathogenesis remains unclear, follicular occlusion, inflammation, and sinus tract formation are thought to be key contributors. We present two patients, a 26-year-old male and a 33-year-old male, with refractory DCS and concomitant hidradenitis suppurativa and acne conglobata who were successfully treated with a combination therapy regimen of bimekizumab, isotretinoin, and oral antibiotics.  .