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March 7, 2026ACS Biomaterials Science & Engineering

Electric Field-Guided Biomimetic Mineralization of Enamel via Interfacial Engineering of Nanostructured HAp/PDA Coatings with Anisotropy and Enhanced Hardness

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Authors

YIYuri IppolitovDGD. L. GoloshchapovTLTatiana Litvinova

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Overview

Research shows enhanced hardness and organized mineral growth in enamel using electric-field assistance, suggesting promising restoration approaches.

Key Points

  • The aim is to explore a method for enhancing enamel by applying electric-field-guided biomimetic mineralization techniques.
  • Utilized electric-field-assisted biomimetic mineralization with isolated electrodes.
  • Employed grazing-incidence X-ray diffraction to confirm hydroxyapatite phase.
  • Used electron microscopy and atomic force microscopy to characterize nanostructures.
  • Implemented machine-learning clustering for analyzing hyperspectral maps.
  • Coating shows a significantly higher microhardness compared to native enamel.
  • Distinct nanoscale chemical heterogeneity identified in the mineral coating.
  • Textured assembly of nanocrystals resulted in enhanced mechanical properties.
  • Electric-field application led to organized coating architecture.

Cite This Study

Ippolitov et al. (2026) studied this question.

synapsesocial.com/papers/69abc1235af8044f7a4e9beehttps://doi.org/10.1021/acsbiomaterials.5c02164
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