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Research Paper | Synapse

March 7, 2026European Journal of Endocrinology0 citations

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Cortisol assays across the physiologic spectrum: Access immunoassay compared with LC-MS/MS

ANAndrew J NewmanBrigham and Women's Hospital SMSanan MahrokhianBrigham and Women's Hospital IHIsabelle HannaTufts University

Key Points

To compare the accuracy of cortisol measurements between immunoassays and LC-MS/MS methods.
Analyzed cortisol levels using both immunoassay and LC-MS/MS techniques.
Evaluated measurement consistency across different physiological states.
Immunoassay results aligned closely with LC-MS/MS measurements.
Both methods yielded reliable cortisol assessments across the physiologic spectrum.

Abstract

Clinicians should be reassured that this immunoassay provides cortisol measurements similar to gold-standard LC-MS/MS across the physiologic continuum.

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Cite This Study

Newman et al. (Wed,) studied this question.

synapsesocial.com/papers/69abc1535af8044f7a4e9dd5 https://doi.org/https://doi.org/10.1093/ejendo/lvag043

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