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March 5, 2026Journal of Turkish Society of Obstetric and GynecologyOpen Access

Inverted microscopy-based assessment reveals major maturation gap between denuded and non-denuded GV oocytes: A novel r-IVM approach

Nuri Peker Ayşen Yücetürk Özge Karaosmanoğlu Esra Tığlı Burak Elmas Ilke Ozer Aslan Burcu Aksu Türan Bülent Tıraş

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Key Points

To evaluate the maturation rates of denuded versus non-denuded GV oocytes using a novel r-IVM approach.
Used inverted microscopy to assess oocyte maturation
Compared denuded and non-denuded GV oocytes
Measured fertilization and embryo development rates
Non-denuded oocytes showed higher maturation rates
Fertilization rates were significantly higher in non-denuded oocytes
Embryo development rates favor non-denuded oocytes

Implication

Inverted microscopy assesses maturation in oocytes, revealing differences that suggest improved fertility outcomes.

Abstract

Non-denuded immature oocytes demonstrated significantly higher maturation, fertilization, and embryo development rates compared with denuded oocytes.

Discussion

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Cite This Study

Peker et al. (2026) studied this question.

synapsesocial.com/papers/69abc1765af8044f7a4ea1cf https://doi.org/10.4274/tjod.galenos.2026.26098

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Inverted microscopy as a high performance tool for pre denudation evaluation of oocyte nuclear maturityIn Vitro Study · 2026
2Microsensors and image processing for single oocyte qualification: toward multiparametric determination of the best time for fertilizationIn Vitro Study · 2013 · 12 citations
3Testing the role of unstimulated ın vitro maturation in the developmental potential of immature oocytes in women with oocyte maturation abnormalities2024
4Treatment of human oocytes with extracellular vesicles from follicular fluid during rescue <i>in vitro</i> maturation enhances maturation rates and modulates oocyte proteome and ultrastructureIn Vitro Study · 2026 · 3 citations
5Treatment of human oocytes with extracellular vesicles from follicular fluid during rescue <i>in vitro</i> maturation enhances maturation rates and modulates oocyte proteome and ultrastructureIn Vitro Study · 2026

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