Both low and high cardiac indices identify high-risk patients with moderate and severe tricuspid regurgitation, whereas an intermediate cardiac index indicates a prognostically favorable state.
Observational
Does Cardiac Index (CI) profiling predict outcomes in patients with moderate and severe tricuspid regurgitation?
Cardiac index profiling in moderate and severe tricuspid regurgitation exhibits a U-shaped prognostic relationship, where both low and high CIs indicate higher risk compared to an intermediate CI.
In moderate and severe TRs, CI profiling captures cardiac and extracardiac determinants of flow and independently predicts outcomes beyond conventional TR grading and staging. Both low and high CIs identify high-risk patients, while an intermediate CI indicates a balanced, prognostically favorable state. CI profiling may refine risk stratification, guide individualized treatment strategies, and optimize patient selection and timing for tricuspid valve interventions.
Raciti et al. (2026) conducted an observational in Moderate and severe tricuspid regurgitation. Cardiac Index (CI) profiling vs. Intermediate CI was evaluated on Outcomes. Both low and high cardiac indices identify high-risk patients with moderate and severe tricuspid regurgitation, whereas an intermediate cardiac index indicates a prognostically favorable state.