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March 1, 2026

Identification of the Novel HLA-A*24:671 Allele by Next-Generation Sequencing.

Dongyi Yu J. Liu

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Key Points

This research aims to identify and characterize the novel HLA-A*24:671 allele through advanced sequencing techniques.
Utilized next-generation sequencing technology
Analyzed genetic sequences for allele identification
Compared HLA-A*24:671 with known alleles such as HLA-A*24:02:01:01
Identified the novel allele HLA-A*24:671
Detected a G>C substitution at cDNA position 239
Established differences between HLA-A*24:671 and HLA-A*24:02:01:01

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Implication

Next-generation sequencing identifies a novel allele variant, HLA-A*24:671, indicating genetic diversity.

Abstract

HLA-A*24:671 differs from HLA-A*24:02:01:01 by a G>C substitution at cDNA position 239.

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Cite This Study

Yu et al. (2026) studied this question.

synapsesocial.com/papers/69ada8c2bc08abd80d5bc094 https://doi.org/10.1111/tan.70632

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Identification of the Novel HLA-A*24:675 Allele by Next-Generation Sequencing.Original Research · 2026 · 2 citations
2A Novel <scp>HLA</scp> ‐A Allele, <i>HLA‐A*24:672</i> , Identified by Next Generation SequencingOriginal Research · 2026 · 2 citations
3The Novel <i>HLA‐A*24:668</i> Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual2025 · 2 citations
4The HLA‐A*24:02:190 Allele Identified by Next‐Generation Sequencing and Confirmed by Nanopore SequencingOriginal Research · 2026
5The novel <i>HLA‐A*24:393</i> allele, identified by <scp>Sanger</scp> dideoxy nucleotide sequencing in a Taiwanese individual2024 · 3 citations
6The novel <i>HLA‐A*24:627</i> allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual2024 · 3 citations
7The novel <i>HLA‐A*24:617</i> allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual2024 · 3 citations
8Characterization of the Novel <i>HLA‐A*24:02:169</i> Allele by Sequencing‐Based Typing2024 · 2 citations

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