Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 29, 2026HLAOpen Access

The HLA‐A*24:02:190 Allele Identified by Next‐Generation Sequencing and Confirmed by Nanopore Sequencing

View Full Paper
Ask AI
Bookmark
Share

Authors

EHElham HarfouchMGMarilyne GomesAHAicha Hamdaoui

Discussion

Loading...

Member takes

Overview

Sequencing report identifies the novel HLA-A*24:02:190 allele with a synonymous exon 4 variation, highlighting expanded diversity in human leukocyte antigen genetics.

Key Points

  • To characterize and validate a novel human leukocyte antigen allele detected during sequence-based typing.
  • Identified the candidate novel allele using next-generation sequencing.
  • Confirmed the full-length allele sequence and single-nucleotide variation using long-read nanopore sequencing.
  • HLA-A*24:02:190 differs from the reference allele HLA-A*24:02:01:01 by a single synonymous nucleotide substitution in exon 4.

Cite This Study

Harfouch et al. (2026) studied this question.

synapsesocial.com/papers/6a9299bb8e5d7d1fc0c11d29https://doi.org/10.1111/tan.70947
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of the Novel HLA-A*24:675 Allele by Next-Generation Sequencing.2026 · 1 citations
  2. 2The novel <i>HLA‐A*24:617</i> allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual2024 · 3 citations
  3. 3The Novel <i>HLA‐A*24:668</i> Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual2025
  4. 4A Novel <scp>HLA</scp> ‐A Allele, <i>HLA‐A*24:672</i> , Identified by Next Generation Sequencing2026 · 2 citations
  5. 5Identification of the Novel HLA-A*24:671 Allele by Next-Generation Sequencing.2026 · 1 citations