Effect of Comprehensive Outpatient Cardiac Rehabilitation on All-Cause Mortality After Transcatheter Aortic Valve Implantation

Figures

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  Central Figure.

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  Figure 1.. Flowchart showing patient disposition in the present study. ADL, activities of daily living; OCR, outpatient cardiac rehabilitation.

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  Figure 2.. Kaplan-Meier curve for all-cause mortality. During a mean follow-up period of 2.9±2.0 years, 331 (22.9%) patients died, and a log-rank test using Kaplan-Meier survival curves before and after propensity score matching (PSM) showed a significant difference between the outpatient cardiac rehabilitation (OCR)-participating groups (P=0.001).

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  Figure 3.. Cardiopulmonary capacity and changes in physical parameters measured pre-rehabilitation and post-rehabilitation program in patients participating in outpatient cardiac rehabilitation (OCR) are shown. Boxes indicate quartile ranges; medians are indicated using horizontal lines, and whiskers indicate ranges. The values below each boxplot are the mean±standard deviation. AT, anaerobic threshold; V̇E/V̇CO2, ventilation equivalent of CO2; V̇O2, oxygen consumption.

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  Figure 4.. Kaplan-Meier curve for all-cause mortality. A log-rank test using Kaplan-Meier curves between the 3 groups of improved outpatient cardiac rehabilitation (OCR), non-improved, and non-OCR participants showed a significant difference in peakV̇O2, gait speed, and knee extension muscle strength with or without improvement (peakV̇O2 P=0.39, gait speed P=0.85, and knee extension muscle strength P=0.94).

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  Figure 5.. Kaplan-Meier survival curves for subgroup analyses in older patients. Among those classified as older at admission (n=494), all-cause mortality was significantly lower in the outpatient cardiac rehabilitation (OCR) group than it was in the non-OCR group (log-rank P=0.004). Within the OCR group, baseline frailty status was not significantly associated with all-cause mortality (log-rank P=0.508).