AI derived ECG global longitudinal strain compared to echocardiographic measurements

Figures

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  Fig. 1. Composition of the training and validation cohorts. Echocardiography and 12-lead electrocardiography (ECG) pairs performed within a 7-day interval were included in the analysis.

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  Fig. 2. Representative case of LVGLS and ECG-GLS score pair. (A) A 43-year-old female who underwent echocardiography for routine checkup. (B) A 78-year-old female with ischemic cardiomyopathy.

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  Fig. 3. ECG-GLS evaluations. (A) In the validation cohort, the LVGLS and ECG-GLS score were significantly correlated (correlation coefficient = 0.64, p < 0.001). (B) Receiver-operating characteristic curves of the ECG-GLS score for the prediction of LVGLS ≤ 12% in the training cohort (blue) and validation cohort (red) are shown. Abbreviations: AUROC, area under the receiver operating characteristic curve; ECG-GLS,electrocardiography-derived global longitudinal strain; LVGLS, left ventricular global longitudinal strain on echocardiography.

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  Fig. 4. Receiver-operating characteristic curves. The performance of the ECG-GLS score (solid line) and LVGLS (dashed line) for the prediction of heart failure with reduced ejection fraction are shown. Abbreviations: AUROC, area under the receiver operating characteristic curve; ECG-GLS,electrocardiography-derived global longitudinal strain; LVGLS, left ventricular global longitudinal strain on echocardiography.

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  Fig. 5. Survival curve comparisons. (A) Event-free survival curves for ACD and the composite outcome of ACD and HHF according to an ECG-GLS score > 12 (blue) and ≤ 12 (red). (B) Event-free survival curves for ACD and the composite outcome of ACD and HHF according to an LVGLS > 12% (green) and ≤ 12% (purple). Abbreviations: ACD, all-cause death; ECG-GLS, electrocardiography-derived global longitudinal strain; HHF, hospitalization for heart failure; LVGLS, left ventricular global longitudinal strain onechocardiography.