Multifunctional nanomotors enhance biofilm penetration and immune modulation in peri-implantitis, suggesting a new therapeutic strategy.
Collectively, this study demonstrates a multifunctional nanomotor-based therapeutic strategy that integrates inflammation-responsive propulsion, enhanced biofilm penetration, mild photothermal disinfection, and immune reprogramming. By harnessing pathological microenvironmental cues as endogenous driving forces, the M-CaO₂-CL nanomotor effectively addresses key biological barriers in peri-implantitis, establishing a promising nanotherapeutic platform for biofilm-associated inflammatory diseases.
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Wang et al. (2026) studied this question.
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